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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human OPA3 HGNC:8142 (HGNC)
80207 (Entrez Gene)
606580 (OMIM)
OPA3 (MyGene.info)
HGNC homology
Chr19 q13.32 Chr19:45527767-45584864 (-)
3-methylglutaconic aciduria type 3
optic atrophy
Q9H6K4 (UniProt | EBI)
NM_001017989 (RefSeq)
mouse Opa3 MGI:2686271 (MGI)
403187 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 9.48 cM Chr7:19228334-19256543 (+)
3-methylglutaconic aciduria type 3
OTTMUSG00000031701 (VEGA)
OTTMUSP00000075012 (VEGA)
OTTMUST00000081591 (VEGA)
cattle OPA3 523579 (Entrez Gene)
Chr18 Q05B66 (UniProt | EBI)
NM_001245934 (RefSeq)
dog OPA3 612263 (Entrez Gene)
zebrafish opa3 497278 (Entrez Gene)
Chr18 Q1L9A2 (UniProt | EBI)
NM_001080166 (RefSeq)
frog, western clawed opa3 100485565 (Entrez Gene)
Chr8 XP_002932648 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory