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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human INPP5E HGNC:21474 (HGNC)
56623 (Entrez Gene)
613037 (OMIM)
HGNC homology
Chr9 q34.3 Chr9:136428615-136439861 (-)
Joubert syndrome 1
Q9NRR6 (UniProt | EBI)
NM_019892 (RefSeq)
mouse Inpp5e MGI:1927753 (MGI)
64436 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 18.88 cM Chr2:26396249-26409203 (-)
OTTMUSG00000012777 (VEGA)
OTTMUSP00000013735 (VEGA)
OTTMUST00000030592 (VEGA)
rat Inpp5e 114089 (Entrez Gene)
Chr3 p13 Q9WVR1 (UniProt | EBI)
NM_053632 (RefSeq)
chimpanzee INPP5E 748603 (Entrez Gene)
Chr9 A0FI79 (UniProt | EBI)
NM_001077513 (RefSeq)
cattle INPP5E 506349 (Entrez Gene)
Chr11 NP_001179019 (RefSeq)
NM_001192090 (RefSeq)
dog INPP5E 607443 (Entrez Gene)
Chr9 XP_022279293 (RefSeq)
chicken INPP5E 417135 (Entrez Gene)
Chr17 XP_415418 (RefSeq)
zebrafish inpp5e 606579 (Entrez Gene)
Chr5 NP_001096089 (RefSeq)
NM_001102619 (RefSeq)
frog, western clawed inpp5e 100486470 (Entrez Gene)
Chr2 XP_002935265 (RefSeq)
macaque, rhesus INPP5E 710121 (Entrez Gene)
Chr15 NP_001180942 (RefSeq)
NM_001194013 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory