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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RRM2B HGNC:17296 (HGNC)
50484 (Entrez Gene)
604712 (OMIM)
HGNC homology
Chr8 q23.1 Chr8:102204501-102239118 (-)
Mitochondrial DNA Depletion Syndrome 8a (encephalomyopathic Type with Renal Tubulopathy); MTDPS8A
Progressive External Ophthalmoplegia with Mitochondrial DNA Deletions, Autosomal Dominant 5; PEOA5
Q7LG56 (UniProt | EBI)
NM_001172478 (RefSeq)
mouse Rrm2b MGI:2155865 (MGI)
382985 (Entrez Gene)
Gene Tree
HGNC homology
Chr15 15.1 cM Chr15:37923952-37961318 (-)
OTTMUSG00000032790 (VEGA)
OTTMUSP00000043707 (VEGA)
OTTMUST00000081651 (VEGA)
rat Rrm2b 299976 (Entrez Gene)
Chr7 q22 NP_001124015 (RefSeq)
NM_001130543 (RefSeq)
chimpanzee RRM2B 472832 (Entrez Gene)
Chr8 XP_009454026 (RefSeq)
cattle RRM2B 528960 (Entrez Gene)
Chr14 XP_010810462 (RefSeq)
dog RRM2B 481988 (Entrez Gene)
Chr13 XP_539109 (RefSeq)
chicken RRM2B 420253 (Entrez Gene)
Chr2 XP_418364 (RefSeq)
western clawed frog rrm2b 100144925 (Entrez Gene)
ChrUN NP_001119973 (RefSeq)
NM_001126501 (RefSeq)
zebrafish rrm2b 368909 (Entrez Gene)
Chr19 NP_001007164 (RefSeq)
NM_001007163 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory