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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
56556

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIRT1 HGNC:14929 (HGNC)
23411 (Entrez Gene)
604479 (OMIM)
Chr10 q21.3 Chr10:67884669-67918390 (+)
GRCh38
Q96EB6 (UniProt | EBI)
NM_012238 (RefSeq)
mouse Sirt1 MGI:2135607 (MGI)
93759 (Entrez Gene)
Gene Tree
VISTA-Point
Chr10 32.57 cM Chr10:63319005-63381704 (-)
GRCm38
Diabetes Insipidus, Nephrogenic, Autosomal
Fatty Liver Disease, Nonalcoholic, Susceptibility to, 1; NAFLD1
OTTMUSG00000030914 (VEGA)
OTTMUSP00000040277 (VEGA)
OTTMUST00000076493 (VEGA)
rat Sirt1 309757 (Entrez Gene)
Chr20 p11 XP_006223939 (RefSeq)
NM_001107627 (RefSeq)
chimpanzee SIRT1 466088 (Entrez Gene)
Chr10 XP_003312628 (RefSeq)
rhesus macaque SIRT1 695682 (Entrez Gene)
Chr9 XP_001087854 (RefSeq)
cattle SIRT1 613629 (Entrez Gene)
Chr28 NP_001179909 (RefSeq)
NM_001192980 (RefSeq)
dog SIRT1 489012 (Entrez Gene)
Chr4 XP_546130 (RefSeq)
chicken SIRT1 423646 (Entrez Gene)
Chr6 NP_001004767 (RefSeq)
NM_001004767 (RefSeq)
western clawed frog sirt1 100145679 (Entrez Gene)
ChrUN NP_001136381 (RefSeq)
NM_001142909 (RefSeq)
zebrafish sirt1 797132 (Entrez Gene)
Chr13 XP_001334440 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory