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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
56469

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DES HGNC:2770 (HGNC)
1674 (Entrez Gene)
125660 (OMIM)
Chr2 q35 Chr2:219418377-219426739 (+)
GRCh38
Cardiomyopathy, Dilated, 1I; CMD1I
Muscular Dystrophy, Limb-Girdle, Type 2r; LGMD2R
Myopathy, Myofibrillar, 1; MFM1
Scapuloperoneal Syndrome, Neurogenic, Kaeser Type; SCPNK
P17661 (UniProt | EBI)
NM_001927 (RefSeq)
mouse Des MGI:94885 (MGI)
13346 (Entrez Gene)
Gene Tree
VISTA-Point
Chr1 38.85 cM Chr1:75360329-75368579 (+)
GRCm38
Cardiomyopathy, Dilated, 1I; CMD1I
Myopathy, Myofibrillar, 1; MFM1
OTTMUSG00000019416 (VEGA)
OTTMUSP00000020924 (VEGA)
OTTMUST00000046346 (VEGA)
rat Des 64362 (Entrez Gene)
Chr9 q33 P48675 (UniProt | EBI)
NM_022531 (RefSeq)
chimpanzee DES 470657 (Entrez Gene)
Chr2B XP_526039 (RefSeq)
rhesus macaque DES 703300 (Entrez Gene)
Chr12 NP_001181195 (RefSeq)
NM_001194266 (RefSeq)
cattle DES 280765 (Entrez Gene)
Chr2 O62654 (UniProt | EBI)
NM_001081575 (RefSeq)
dog DES 497091 (Entrez Gene)
Chr37 Q5XFN2 (UniProt | EBI)
NM_001012394 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory