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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
56379

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human APP HGNC:620 (HGNC)
351 (Entrez Gene)
104760 (OMIM)
Chr21 q21.3 Chr21:25880550-26171128 (-)
GRCh38
Alzheimer Disease; AD
Cerebral Amyloid Angiopathy, App-Related
P05067 (UniProt | EBI)
NM_000484 (RefSeq)
mouse App MGI:88059 (MGI)
11820 (Entrez Gene)
Gene Tree
VISTA-Point
Chr16 46.92 cM Chr16:84954440-85173707 (-)
GRCm38
Alzheimer Disease; AD
ENSMUSG00000022892 (Ensembl Gene Model)
ENSMUSP00000005406 (Ensembl)
ENSMUST00000005406 (Ensembl)
rat App 54226 (Entrez Gene)
Chr11 q11 P08592 (UniProt | EBI)
NM_019288 (RefSeq)
chimpanzee APP 473931 (Entrez Gene)
Chr21 Q5IS80 (UniProt | EBI)
NM_001013018 (RefSeq)
rhesus macaque APP 100427716 (Entrez Gene)
Chr3 P29216 (UniProt | EBI)
dog APP 403407 (Entrez Gene)
Chr31 Q28280 (UniProt | EBI)
NM_001006601 (RefSeq)
chicken APP 374198 (Entrez Gene)
Chr1 NP_989639 (RefSeq)
NM_204308 (RefSeq)
western clawed frog app 448208 (Entrez Gene)
ChrUN NP_001005698 (RefSeq)
NM_001005698 (RefSeq)
zebrafish appb 170846 (Entrez Gene)
Chr9 NP_690842 (RefSeq)
NM_152886 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory