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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ALOX5 HGNC:435 (HGNC)
240 (Entrez Gene)
152390 (OMIM)
Arachidonate 5-lipoxygenase (MyGene.info)
HGNC homology
Chr10 q11.21 Chr10:45374166-45446121 (+)
P09917 (UniProt | EBI)
NM_001256154 (RefSeq)
mouse Alox5 MGI:87999 (MGI)
11689 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 53.79 cM Chr6:116410077-116461178 (-)
OTTMUSG00000036516 (VEGA)
OTTMUSP00000051997 (VEGA)
OTTMUST00000093640 (VEGA)
rat Alox5 25290 (Entrez Gene)
Chr4 q42 P12527 (UniProt | EBI)
NM_012822 (RefSeq)
chimpanzee ALOX5 450428 (Entrez Gene)
Chr10 XP_016773660 (RefSeq)
cattle ALOX5 404074 (Entrez Gene)
Chr28 NP_001179721 (RefSeq)
NM_001192792 (RefSeq)
dog ALOX5 477753 (Entrez Gene)
Chr28 NP_001192042 (RefSeq)
NM_001205113 (RefSeq)
chicken ALOX5 423769 (Entrez Gene)
Chr6 XP_003641560 (RefSeq)
zebrafish alox5a 567204 (Entrez Gene)
Chr13 NP_001290191 (RefSeq)
NM_001256747 (RefSeq)
frog, western clawed alox5 100036609 (Entrez Gene)
Chr7 XP_004915982 (RefSeq)
macaque, rhesus ALOX5 707926 (Entrez Gene)
Chr9 XP_001102354 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory