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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human VPS54 HGNC:18652 (HGNC)
51542 (Entrez Gene)
614633 (OMIM)
HGNC homology
Chr2 p15-p14 Chr2:63892149-64019421 (-)
Q9P1Q0 (UniProt | EBI)
NM_016516 (RefSeq)
mouse Vps54 MGI:2178798 (MGI)
245944 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 13.89 cM Chr11:21239281-21321136 (+)
amyotrophic lateral sclerosis type 1
Werdnig-Hoffmann disease
OTTMUSG00000005242 (VEGA)
OTTMUSP00000005421 (VEGA)
OTTMUST00000011688 (VEGA)
rat Vps54 286932 (Entrez Gene)
Chr14 q22 Q9JMK8 (UniProt | EBI)
NM_173147 (RefSeq)
chimpanzee VPS54 459274 (Entrez Gene)
Chr2A XP_016804113 (RefSeq)
cattle VPS54 783762 (Entrez Gene)
Chr11 NP_001098930 (RefSeq)
NM_001105460 (RefSeq)
dog VPS54 474616 (Entrez Gene)
Chr10 XP_005626212 (RefSeq)
chicken VPS54 421280 (Entrez Gene)
Chr3 XP_419349 (RefSeq)
zebrafish vps54 562169 (Entrez Gene)
Chr1 NP_001124248 (RefSeq)
NM_001130776 (RefSeq)
frog, western clawed vps54 100380095 (Entrez Gene)
Chr5 XP_017949656 (RefSeq)
macaque, rhesus VPS54 695397 (Entrez Gene)
Chr13 NP_001247947 (RefSeq)
NM_001261018 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory