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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RIT1 HGNC:10023 (HGNC)
6016 (Entrez Gene)
609591 (OMIM)
RIT1 (MyGene.info)
HGNC homology
Chr1 q22 Chr1:155897808-155911402 (-)
Noonan syndrome 8
Q92963 (UniProt | EBI)
NM_001256821 (RefSeq)
mouse Rit1 MGI:108053 (MGI)
19769 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 38.95 cM Chr3:88716841-88731048 (+)
19769 (NCBI Gene Model)
P70426 (UniProt | EBI)
NR_028056 (RefSeq)
rat Rit1 499652 (Entrez Gene)
Chr2 q34 NP_001102655 (RefSeq)
NM_001109185 (RefSeq)
chimpanzee RIT1 457377 (Entrez Gene)
Chr1 XP_009432240 (RefSeq)
cattle RIT1 533646 (Entrez Gene)
Chr3 NP_001091547 (RefSeq)
NM_001098078 (RefSeq)
dog RIT1 480126 (Entrez Gene)
Chr7 XP_537249 (RefSeq)
chicken RIT1 425068 (Entrez Gene)
Chr25 NP_001026498 (RefSeq)
NM_001031327 (RefSeq)
zebrafish rit1 793942 (Entrez Gene)
Chr19 NP_001122253 (RefSeq)
NM_001128781 (RefSeq)
frog, western clawed rit1 100486360 (Entrez Gene)
ChrUN XP_002944039 (RefSeq)
macaque, rhesus RIT1 717985 (Entrez Gene)
Chr1 NP_001248730 (RefSeq)
NM_001261801 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory