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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MTHFD1 HGNC:7432 (HGNC)
4522 (Entrez Gene)
172460 (OMIM)
MTHFD1 (MyGene.info)
HGNC homology
Chr14 q23.3 Chr14:64388041-64460007 (+)
neural tube defect
P11586 (UniProt | EBI)
NM_001364837 (RefSeq)
mouse Mthfd1 MGI:1342005 (MGI)
108156 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 33.52 cM Chr12:76255298-76319803 (+)
ENSMUSG00000021048 (Ensembl Gene Model)
ENSMUSP00000021443 (Ensembl)
ENSMUST00000021443 (Ensembl)
rat Mthfd1 64300 (Entrez Gene)
Chr6 q24 P27653 (UniProt | EBI)
NM_022508 (RefSeq)
chimpanzee MTHFD1 452965 (Entrez Gene)
Chr14 XP_016781707 (RefSeq)
cattle MTHFD1 534382 (Entrez Gene)
Chr10 NP_001076946 (RefSeq)
NM_001083477 (RefSeq)
dog MTHFD1 480352 (Entrez Gene)
Chr8 XP_005623549 (RefSeq)
chicken MTHFD1 423508 (Entrez Gene)
Chr5 NP_001034392 (RefSeq)
NM_001039303 (RefSeq)
zebrafish mthfd1b 260441 (Entrez Gene)
Chr17 NP_955823 (RefSeq)
NM_199529 (RefSeq)
frog, western clawed mthfd1 493369 (Entrez Gene)
Chr8 NP_001008007 (RefSeq)
NM_001008006 (RefSeq)
macaque, rhesus MTHFD1 707059 (Entrez Gene)
Chr7 XP_014999368 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory