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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ROCK1 HGNC:10251 (HGNC)
6093 (Entrez Gene)
601702 (OMIM)
ROCK1 (MyGene.info)
HGNC homology
Chr18 q11.1 Chr18:20949740-21111851 (-)
Q13464 (UniProt | EBI)
NM_005406 (RefSeq)
mouse Rock1 MGI:107927 (MGI)
19877 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 4.91 cM Chr18:10064401-10181792 (-)
19877 (NCBI Gene Model)
P70335 (UniProt | EBI)
NM_009071 (RefSeq)
rat Rock1 81762 (Entrez Gene)
Chr18 p13 Q63644 (UniProt | EBI)
NM_031098 (RefSeq)
chimpanzee ROCK1 455326 (Entrez Gene)
Chr18 P61584 (UniProt | EBI)
cattle ROCK1 785911 (Entrez Gene)
Chr24 Q8MIT6 (UniProt | EBI)
NM_001191227 (RefSeq)
dog ROCK1 480181 (Entrez Gene)
Chr7 XP_005623079 (RefSeq)
chicken ROCK1 373970 (Entrez Gene)
Chr2 NP_001186377 (RefSeq)
NM_001199448 (RefSeq)
zebrafish rock1 100329779 (Entrez Gene)
Chr2 NP_001243563 (RefSeq)
NM_001256634 (RefSeq)
frog, western clawed rock1 100496057 (Entrez Gene)
Chr6 XP_002934180 (RefSeq)
macaque, rhesus ROCK1 698223 (Entrez Gene)
Chr18 NP_001248063 (RefSeq)
NM_001261134 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory