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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CDKL5 HGNC:11411 (HGNC)
6792 (Entrez Gene)
300203 (OMIM)
HGNC homology
ChrX p22.13 ChrX:18425605-18660858 (+)
Epileptic Encephalopathy, Early Infantile, 2; EIEE2
O76039 (UniProt | EBI)
NM_001323289 (RefSeq)
mouse Cdkl5 MGI:1278336 (MGI)
382253 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 73.95 cM ChrX:160771923-160994704 (-)
Epileptic Encephalopathy, Early Infantile, 2; EIEE2
OTTMUSG00000019591 (VEGA)
OTTMUSP00000071880 (VEGA)
OTTMUST00000136003 (VEGA)
rat Cdkl5 100362725 (Entrez Gene)
ChrX XP_017443712 (RefSeq)
chimpanzee CDKL5 473529 (Entrez Gene)
ChrX XP_016798673 (RefSeq)
cattle CDKL5 538337 (Entrez Gene)
ChrX XP_015317258 (RefSeq)
dog CDKL5 491761 (Entrez Gene)
ChrX XP_013967109 (RefSeq)
chicken CDKL5 428001 (Entrez Gene)
Chr1 XP_015128387 (RefSeq)
zebrafish cdkl5 559341 (Entrez Gene)
Chr11 NP_001139240 (RefSeq)
NM_001130771 (RefSeq)
frog, western clawed cdkl5 100145195 (Entrez Gene)
Chr2 XP_004911817 (RefSeq)
macaque, rhesus CDKL5 693974 (Entrez Gene)
ChrX XP_002808564 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.06
The Jackson Laboratory