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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CDKL5 HGNC:11411 (HGNC)
6792 (Entrez Gene)
300203 (OMIM)
HGNC homology
ChrX p22 ChrX:18425605-18660858 (+)
Angelman Syndrome; AS
Epileptic Encephalopathy, Early Infantile, 2; EIEE2
O76039 (UniProt | EBI)
NM_001037343 (RefSeq)
mouse Cdkl5 MGI:1278336 (MGI)
382253 (Entrez Gene)
Gene Tree
ChrX 73.95 cM ChrX:160771923-160994704 (-)
Epileptic Encephalopathy, Early Infantile, 2; EIEE2
OTTMUSG00000019591 (VEGA)
OTTMUSP00000071880 (VEGA)
OTTMUST00000136003 (VEGA)
rat Cdkl5 100362725 (Entrez Gene)
ChrX XP_006227387 (RefSeq)
chimpanzee CDKL5 473529 (Entrez Gene)
ChrX XP_009437110 (RefSeq)
rhesus macaque CDKL5 693974 (Entrez Gene)
ChrX XP_002808564 (RefSeq)
cattle CDKL5 538337 (Entrez Gene)
ChrX XP_002707463 (RefSeq)
dog CDKL5 491761 (Entrez Gene)
ChrX XP_013967110 (RefSeq)
chicken CDKL5 428001 (Entrez Gene)
Chr1 XP_425571 (RefSeq)
western clawed frog cdkl5 100145195 (Entrez Gene)
ChrUN XP_012813099 (RefSeq)
zebrafish cdkl5 559341 (Entrez Gene)
Chr11 NP_001139240 (RefSeq)
NM_001145768 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory