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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MAP2K6 HGNC:6846 (HGNC)
5608 (Entrez Gene)
601254 (OMIM)
MAP2K6 (MyGene.info)
HGNC homology
Chr17 q24.3 Chr17:69414697-69553854 (+)
P52564 (UniProt | EBI)
NM_001330450 (RefSeq)
mouse Map2k6 MGI:1346870 (MGI)
26399 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 73.6 cM Chr11:110399103-110516201 (+)
26399 (NCBI Gene Model)
P70236 (UniProt | EBI)
NM_001356345 (RefSeq)
rat Map2k6 114495 (Entrez Gene)
Chr10 q32.1 NP_446155 (RefSeq)
NM_053703 (RefSeq)
chimpanzee MAP2K6 468310 (Entrez Gene)
Chr17 XP_009431432 (RefSeq)
cattle MAP2K6 286883 (Entrez Gene)
Chr19 Q5E9X2 (UniProt | EBI)
NM_001034045 (RefSeq)
dog MAP2K6 480454 (Entrez Gene)
Chr9 XP_022278578 (RefSeq)
chicken MAP2K6 417445 (Entrez Gene)
Chr18 XP_003642396 (RefSeq)
zebrafish map2k6 65239 (Entrez Gene)
Chr12 Q9DGE0 (UniProt | EBI)
NM_001312870 (RefSeq)
frog, western clawed map2k6 448132 (Entrez Gene)
Chr10 NP_001005653 (RefSeq)
NM_001005653 (RefSeq)
macaque, rhesus MAP2K6 693914 (Entrez Gene)
Chr16 NP_001248635 (RefSeq)
NM_001261706 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory