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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
55671

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLCG2 HGNC:9066 (HGNC)
5336 (Entrez Gene)
600220 (OMIM)
Chr16 q24.1 Chr16:81779294-81958294 (+)
GRCh38
Autoinflammation, Antibody Deficiency, and Immune Dysregulation, Plcg2-Associated;
Familial Cold Autoinflammatory Syndrome 3; FCAS3
P16885 (UniProt | EBI)
NM_002661 (RefSeq)
mouse Plcg2 MGI:97616 (MGI)
234779 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 64.26 cM Chr8:117498291-117635140 (+)
GRCm38
ENSMUSG00000034330 (Ensembl Gene Model)
ENSMUSP00000079991 (Ensembl)
ENSMUST00000081232 (Ensembl)
rat Plcg2 29337 (Entrez Gene)
Chr19 q12 P24135 (UniProt | EBI)
NM_017168 (RefSeq)
chimpanzee PLCG2 454268 (Entrez Gene)
Chr16 XP_001148089 (RefSeq)
rhesus macaque PLCG2 714173 (Entrez Gene)
Chr20 XP_001111717 (RefSeq)
cattle PLCG2 100337091 (Entrez Gene)
Chr18 XP_003583412 (RefSeq)
dog PLCG2 489692 (Entrez Gene)
Chr5 XP_546812 (RefSeq)
chicken PLCG2 415805 (Entrez Gene)
Chr11 XP_414166 (RefSeq)
zebrafish plcg2 561747 (Entrez Gene)
Chr18 NP_001038433 (RefSeq)
NM_001044968 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory