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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLCG2 HGNC:9066 (HGNC)
5336 (Entrez Gene)
600220 (OMIM)
PLCG2 (MyGene.info)
HGNC homology
Chr16 q23.3 Chr16:81779258-81962693 (+)
familial cold autoinflammatory syndrome 3
P16885 (UniProt | EBI)
NM_002661 (RefSeq)
mouse Plcg2 MGI:97616 (MGI)
234779 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 64.26 cM Chr8:117498291-117635142 (+)
OTTMUSG00000061722 (VEGA)
OTTMUSP00000078104 (VEGA)
OTTMUST00000150630 (VEGA)
rat Plcg2 29337 (Entrez Gene)
Chr19 q12 P24135 (UniProt | EBI)
NM_017168 (RefSeq)
chimpanzee PLCG2 454268 (Entrez Gene)
Chr16 XP_016785730 (RefSeq)
cattle PLCG2 100337091 (Entrez Gene)
Chr18 XP_015322760 (RefSeq)
dog PLCG2 489692 (Entrez Gene)
Chr5 XP_005620714 (RefSeq)
chicken PLCG2 415805 (Entrez Gene)
Chr11 XP_414166 (RefSeq)
zebrafish plcg2 561747 (Entrez Gene)
Chr18 NP_001038433 (RefSeq)
NM_001044968 (RefSeq)
frog, western clawed plcg2 100496686 (Entrez Gene)
Chr4 XP_002934994 (RefSeq)
macaque, rhesus PLCG2 714173 (Entrez Gene)
Chr20 XP_001111717 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory