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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KPNA1 HGNC:6394 (HGNC)
3836 (Entrez Gene)
600686 (OMIM)
Karyopherin alpha 1 (MyGene.info)
HGNC homology
Chr3 q21.1 Chr3:122421901-122514939 (-)
P52294 (UniProt | EBI)
NM_002264 (RefSeq)
mouse Kpna1 MGI:103560 (MGI)
16646 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 25.43 cM Chr16:35983363-36037136 (+)
16646 (NCBI Gene Model)
Q60960 (UniProt | EBI)
NM_008465 (RefSeq)
rat Kpna1 288064 (Entrez Gene)
Chr11 q22 P83953 (UniProt | EBI)
NM_198726 (RefSeq)
chimpanzee KPNA1 460631 (Entrez Gene)
Chr3 XP_001167086 (RefSeq)
cattle KPNA1 539679 (Entrez Gene)
Chr1 A2VE08 (UniProt | EBI)
NM_001081733 (RefSeq)
dog KPNA1 478585 (Entrez Gene)
Chr33 XP_022269727 (RefSeq)
chicken KPNA1 418271 (Entrez Gene)
Chr1 Q5ZML1 (UniProt | EBI)
NM_001030774 (RefSeq)
zebrafish kpna1 572542 (Entrez Gene)
Chr24 XP_701359 (RefSeq)
frog, western clawed kpna1 394800 (Entrez Gene)
ChrUN NP_989192 (RefSeq)
NM_203861 (RefSeq)
macaque, rhesus KPNA1 692082 (Entrez Gene)
Chr2 NP_001248099 (RefSeq)
NM_001261170 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory