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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPEG HGNC:16901 (HGNC)
10290 (Entrez Gene)
615950 (OMIM)
SPEG (MyGene.info)
HGNC homology
Chr2 q35 Chr2:219434215-219493632 (+)
centronuclear myopathy 5
Q15772 (UniProt | EBI)
NM_001173476 (RefSeq)
mouse Speg MGI:109282 (MGI)
11790 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 38.88 cM Chr1:75375297-75432320 (+)
11790 (NCBI Gene Model)
Q62407 (UniProt | EBI)
NM_007463 (RefSeq)
rat Speg 363256 (Entrez Gene)
Chr9 q33 Q63638 (UniProt | EBI)
NM_001108802 (RefSeq)
chimpanzee SPEG 743624 (Entrez Gene)
Chr2B NP_001166952 (RefSeq)
NM_001173481 (RefSeq)
cattle SPEG 523490 (Entrez Gene)
Chr2 NP_001135957 (RefSeq)
NM_001142485 (RefSeq)
dog SPEG 478924 (Entrez Gene)
Chr37 NP_001166949 (RefSeq)
NM_001173478 (RefSeq)
chicken SPEG 429033 (Entrez Gene)
Chr7 XP_015145593 (RefSeq)
zebrafish spegb 563174 (Entrez Gene)
Chr9 XP_009303170 (RefSeq)
frog, western clawed speg 100486621 (Entrez Gene)
Chr9 XP_017952795 (RefSeq)
macaque, rhesus SPEG 703645 (Entrez Gene)
Chr12 XP_014966621 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory