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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EN2 HGNC:3343 (HGNC)
2020 (Entrez Gene)
131310 (OMIM)
HGNC homology
Chr7 q36 Chr7:155458129-155464831 (+)
P19622 (UniProt | EBI)
NM_001427 (RefSeq)
mouse En2 MGI:95390 (MGI)
13799 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 13.94 cM Chr5:28165694-28172166 (+)
OTTMUSG00000037277 (VEGA)
OTTMUSP00000053701 (VEGA)
OTTMUST00000096171 (VEGA)
rat En2 499964 (Entrez Gene)
Chr4 q11 NP_001102684 (RefSeq)
NM_001109214 (RefSeq)
chimpanzee EN2 742707 (Entrez Gene)
Chr7 XP_001146034 (RefSeq)
rhesus macaque EN2 716307 (Entrez Gene)
Chr3 XP_001106130 (RefSeq)
chicken EN2 100859435 (Entrez Gene)
Chr2 Q05917 (UniProt | EBI)
NM_001267719 (RefSeq)
western clawed frog en2 100498251 (Entrez Gene)
ChrUN XP_002932525 (RefSeq)
zebrafish eng2a 30243 (Entrez Gene)
Chr7 P09015 (UniProt | EBI)
NM_131044 (RefSeq)
eng2b 30238 (Entrez Gene)
Chr2 P31533 (UniProt | EBI)
NM_131040 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory