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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DYRK1A HGNC:3091 (HGNC)
1859 (Entrez Gene)
600855 (OMIM)
DYRK1A (MyGene.info)
HGNC homology
Chr21 q22.13 Chr21:37365790-37515376 (+)
autosomal dominant non-syndromic intellectual disability 7
Q13627 (UniProt | EBI)
NM_101395 (RefSeq)
mouse Dyrk1a MGI:1330299 (MGI)
13548 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 55.3 cM Chr16:94570010-94695067 (+)
Down syndrome
OTTMUSG00000028435 (VEGA)
OTTMUSP00000035913 (VEGA)
OTTMUST00000070459 (VEGA)
rat Dyrk1a 25255 (Entrez Gene)
Chr11 q11 Q63470 (UniProt | EBI)
NM_012791 (RefSeq)
chimpanzee DYRK1A 458545 (Entrez Gene)
Chr21 XP_016794025 (RefSeq)
cattle DYRK1A 532989 (Entrez Gene)
Chr1 NP_001192943 (RefSeq)
NM_001206014 (RefSeq)
dog DYRK1A 487755 (Entrez Gene)
Chr31 XP_022269033 (RefSeq)
chicken DYRK1A 395233 (Entrez Gene)
Chr1 NP_989881 (RefSeq)
NM_204550 (RefSeq)
zebrafish dyrk1aa 100005019 (Entrez Gene)
Chr10 NP_001074158 (RefSeq)
NM_001347739 (RefSeq)
frog, western clawed dyrk1a 779733 (Entrez Gene)
Chr2 Q0IJ08 (UniProt | EBI)
NM_001078812 (RefSeq)
macaque, rhesus DYRK1A 693812 (Entrez Gene)
Chr3 NP_001245072 (RefSeq)
NM_001258143 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory