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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GNAS HGNC:4392 (HGNC)
2778 (Entrez Gene)
139320 (OMIM)
GNAS complex locus (MyGene.info)
HGNC homology
Chr20 q13.32 Chr20:58839681-58911196 (+)
Albright's hereditary osteodystrophy
growth hormone secreting pituitary adenoma
McCune Albright syndrome
P84996 (UniProt | EBI)
NM_001309883 (RefSeq)
mouse Gnas MGI:95777 (MGI)
14683 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 97.89 cM Chr2:174284320-174346744 (+)
Albright's hereditary osteodystrophy
OTTMUSG00000016388 (VEGA)
OTTMUSP00000017632 (VEGA)
OTTMUST00000039462 (VEGA)
rat Gnas 24896 (Entrez Gene)
Chr3 q43 P63095 (UniProt | EBI)
NM_019132 (RefSeq)
chimpanzee GNAS 469986 (Entrez Gene)
Chr20 XP_016793678 (RefSeq)
cattle GNAS 281793 (Entrez Gene)
Chr13 q22 O18979 (UniProt | EBI)
NM_001271771 (RefSeq)
dog GNAS 403943 (Entrez Gene)
Chr24 P63091 (UniProt | EBI)
NM_001003263 (RefSeq)
chicken GNAS 419313 (Entrez Gene)
Chr20 XP_024998120 (RefSeq)
zebrafish gnas 557353 (Entrez Gene)
Chr6 XP_005172181 (RefSeq)
frog, western clawed gnas 407931 (Entrez Gene)
ChrUN XP_012810204 (RefSeq)
NM_213690 (RefSeq)
macaque, rhesus LOC694289 694289 (Entrez Gene)
Chr10 XP_015004192 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory