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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
55534

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GNAS HGNC:4392 (HGNC)
2778 (Entrez Gene)
139320 (OMIM)
Chr20 q13.3 Chr20:58839740-58911195 (+)
GRCh38
Acth-Independent Macronodular Adrenal Hyperplasia; AIMAH
McCune-Albright Syndrome; MAS
Osseous Heteroplasia, Progressive; POH
Pituitary Adenoma, Growth Hormone-Secreting
Pseudohypoparathyroidism, Type IA; PHP1A
Pseudohypoparathyroidism, Type IB; PHP1B
Pseudohypoparathyroidism, Type Ic; PHP1C
Pseudopseudohypoparathyroidism; PPHP
O95467 (UniProt | EBI)
NM_000516 (RefSeq)
mouse Gnas MGI:95777 (MGI)
14683 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 97.89 cM Chr2:174284320-174346744 (+)
GRCm38
Pseudohypoparathyroidism, Type IA; PHP1A
Pseudohypoparathyroidism, Type IB; PHP1B
Pseudopseudohypoparathyroidism; PPHP
OTTMUSG00000016388 (VEGA)
OTTMUSP00000017632 (VEGA)
OTTMUST00000039462 (VEGA)
rat Gnas 24896 (Entrez Gene)
Chr3 q42 P63095 (UniProt | EBI)
NM_001024823 (RefSeq)
chimpanzee GNAS 469986 (Entrez Gene)
Chr20 XP_001138016 (RefSeq)
rhesus macaque GNAS 694289 (Entrez Gene)
Chr10 XP_001083221 (RefSeq)
cattle GNAS 281793 (Entrez Gene)
Chr13 q22 O18979 (UniProt | EBI)
NM_181021 (RefSeq)
dog GNAS 403943 (Entrez Gene)
Chr24 P63091 (UniProt | EBI)
NM_001003263 (RefSeq)
chicken GNAS 419313 (Entrez Gene)
Chr20 XP_417485 (RefSeq)
zebrafish gnas 557353 (Entrez Gene)
Chr6 XP_001335732 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory