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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CACNA1C HGNC:1390 (HGNC)
775 (Entrez Gene)
114205 (OMIM)
Chr12 p13.3 Chr12:1970786-2697949 (+)
Brugada Syndrome 3; BRGDA3
Timothy Syndrome; TS
Q13936 (UniProt | EBI)
NM_000719 (RefSeq)
mouse Cacna1c MGI:103013 (MGI)
12288 (Entrez Gene)
Gene Tree
Chr6 55.86 cM Chr6:118587240-119196418 (-)
Timothy Syndrome; TS
OTTMUSG00000049004 (VEGA)
OTTMUSP00000067978 (VEGA)
OTTMUST00000125322 (VEGA)
rat Cacna1c 24239 (Entrez Gene)
Chr4 q42 P22002 (UniProt | EBI)
NM_012517 (RefSeq)
chimpanzee LOC466914 466914 (Entrez Gene)
Chr12 XP_009422893 (RefSeq)
rhesus macaque CACNA1C 721721 (Entrez Gene)
Chr11 XP_001117926 (RefSeq)
dog CACNA1C 403516 (Entrez Gene)
Chr27 XP_005637432 (RefSeq)
chicken CACNA1C 395891 (Entrez Gene)
Chr1 O73707 (UniProt | EBI)
western clawed frog cacna1c 100488055 (Entrez Gene)
ChrUN XP_002938148 (RefSeq)
zebrafish cacna1c 170581 (Entrez Gene)
Chr4 NP_571975 (RefSeq)
NM_131900 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory