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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NOS2 HGNC:7873 (HGNC)
4843 (Entrez Gene)
163730 (OMIM)
HGNC homology
Chr17 q11.2 Chr17:27756766-27804339 (-)
essential hypertension
P35228 (UniProt | EBI)
NM_000625 (RefSeq)
mouse Nos2 MGI:97361 (MGI)
18126 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 46.74 cM Chr11:78920787-78960232 (+)
type 1 diabetes mellitus
18126 (NCBI Gene Model)
P29477 (UniProt | EBI)
NM_010927 (RefSeq)
rat LOC497963 497963 (Entrez Gene)
Chr10 q25 XP_006247011 (RefSeq)
Nos2 24599 (Entrez Gene)
Chr10 q25 Q06518 (UniProt | EBI)
NM_012611 (RefSeq)
chimpanzee NOS2 455026 (Entrez Gene)
Chr17 XP_024206443 (RefSeq)
cattle NOS2 282876 (Entrez Gene)
Chr19 Q27995 (UniProt | EBI)
NM_001076799 (RefSeq)
dog NOS2 403822 (Entrez Gene)
Chr9 O62699 (UniProt | EBI)
NM_001003186 (RefSeq)
chicken NOS2 395807 (Entrez Gene)
Chr19 Q90703 (UniProt | EBI)
NM_204961 (RefSeq)
zebrafish nos2a 404036 (Entrez Gene)
Chr5 NP_001098407 (RefSeq)
NM_001104937 (RefSeq)
nos2b 563654 (Entrez Gene)
Chr15 NP_001106973 (RefSeq)
NM_001113501 (RefSeq)
frog, western clawed nos2 100494698 (Entrez Gene)
Chr2 XP_017946980 (RefSeq)
macaque, rhesus NOS2 706921 (Entrez Gene)
Chr16 O46660 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory