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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CFTR HGNC:1884 (HGNC)
1080 (Entrez Gene)
602421 (OMIM)
HGNC homology
Chr7 q31.2 Chr7:117478367-117668665 (+)
cystic fibrosis
P13569 (UniProt | EBI)
NM_000492 (RefSeq)
mouse Cftr MGI:88388 (MGI)
12638 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 8.1 cM Chr6:18170687-18322768 (+)
cystic fibrosis
OTTMUSG00000024173 (VEGA)
OTTMUSP00000028741 (VEGA)
OTTMUST00000059141 (VEGA)
rat Cftr 24255 (Entrez Gene)
Chr4 q21 P34158 (UniProt | EBI)
NM_031506 (RefSeq)
chimpanzee CFTR 463674 (Entrez Gene)
Chr7 Q2QLE5 (UniProt | EBI)
NM_001079917 (RefSeq)
cattle CFTR 281067 (Entrez Gene)
Chr4 q23-q25 P35071 (UniProt | EBI)
NM_174018 (RefSeq)
dog CFTR 492302 (Entrez Gene)
Chr14 Q5U820 (UniProt | EBI)
NM_001007143 (RefSeq)
chicken CFTR 100049619 (Entrez Gene)
Chr1 NP_001099136 (RefSeq)
NM_001105666 (RefSeq)
zebrafish cftr 559080 (Entrez Gene)
Chr18 Q1LX78 (UniProt | EBI)
NM_001044883 (RefSeq)
frog, western clawed cftr 100486085 (Entrez Gene)
Chr3 XP_012815406 (RefSeq)
macaque, rhesus CFTR 574346 (Entrez Gene)
Chr3 Q00553 (UniProt | EBI)
NM_001032938 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory