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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
55465

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CFTR HGNC:1884 (HGNC)
1080 (Entrez Gene)
602421 (OMIM)
Chr7 q31.2 Chr7:117470772-117668665 (+)
GRCh38
Bronchiectasis with or without Elevated Sweat Chloride 1; BESC1
Cystic Fibrosis; CF
Pancreatitis, Hereditary; PCTT
Vas Deferens, Congenital Bilateral Aplasia Of; CBAVD
P13569 (UniProt | EBI)
NM_000492 (RefSeq)
mouse Cftr MGI:88388 (MGI)
12638 (Entrez Gene)
Gene Tree
VISTA-Point
Chr6 8.1 cM Chr6:18170687-18322768 (+)
GRCm38
Cystic Fibrosis; CF
OTTMUSG00000024173 (VEGA)
OTTMUSP00000028741 (VEGA)
OTTMUST00000059141 (VEGA)
rat Cftr 24255 (Entrez Gene)
Chr4 q21 P34158 (UniProt | EBI)
NM_031506 (RefSeq)
chimpanzee CFTR 463674 (Entrez Gene)
Chr7 Q2QLE5 (UniProt | EBI)
NM_001079917 (RefSeq)
rhesus macaque CFTR 574346 (Entrez Gene)
Chr3 Q00553 (UniProt | EBI)
NM_001032938 (RefSeq)
dog CFTR 492302 (Entrez Gene)
Chr14 Q5U820 (UniProt | EBI)
NM_001007143 (RefSeq)
chicken CFTR 100049619 (Entrez Gene)
Chr1 NP_001099136 (RefSeq)
NM_001105666 (RefSeq)
zebrafish cftr 559080 (Entrez Gene)
Chr18 NP_001038348 (RefSeq)
NM_001044883 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory