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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human KRT5 HGNC:6442 (HGNC)
3852 (Entrez Gene)
148040 (OMIM)
Chr12 q13.13 Chr12:52514575-52520459 (-)
Dowling-Degos Disease 1; DDD1
Epidermolysis Bullosa Simplex, Autosomal Recessive 1; EBSB1
Epidermolysis Bullosa Simplex, Dowling-Meara Type
Epidermolysis Bullosa Simplex, Generalized
Epidermolysis Bullosa Simplex, Localized
Epidermolysis Bullosa Simplex with Migratory Circinate Erythema
Epidermolysis Bullosa Simplex with Mottled Pigmentation; EBS-MP
P13647 (UniProt | EBI)
NM_000424 (RefSeq)
mouse Krt5 MGI:96702 (MGI)
110308 (Entrez Gene)
Gene Tree
Chr15 56.98 cM Chr15:101707070-101712891 (-)
Epidermolysis Bullosa Simplex, Dowling-Meara Type
OTTMUSG00000028033 (VEGA)
OTTMUSP00000035258 (VEGA)
OTTMUST00000069431 (VEGA)
rat Krt5 369017 (Entrez Gene)
Chr7 Q6P6Q2 (UniProt | EBI)
NM_183333 (RefSeq)
rhesus macaque LOC100424400 100424400 (Entrez Gene)
Chr11 XP_002798641 (RefSeq)
cattle KRT5 281268 (Entrez Gene)
Chr5 q14-q23 P04261 (UniProt | EBI)
NM_001008663 (RefSeq)
dog KRT5 100687760 (Entrez Gene)
Chr27 XP_003433559 (RefSeq)
chicken KRT5 407779 (Entrez Gene)
ChrLGE22C19 NP_001001195 (RefSeq)
NM_001001195 (RefSeq)
western clawed frog krt5.2 779830 (Entrez Gene)
ChrUN NP_001072377 (RefSeq)
NM_001078909 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory