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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ITGB3 HGNC:6156 (HGNC)
3690 (Entrez Gene)
173470 (OMIM)
HGNC homology
Chr17 q21.32 Chr17:47253842-47312711 (+)
Bleeding Disorder, Platelet-Type, 16; BDPLT16
Glanzmann Thrombasthenia; GT
Integrin, Beta-3; ITGB3
Myocardial Infarction, Susceptibility to
P05106 (UniProt | EBI)
NM_000212 (RefSeq)
mouse Itgb3 MGI:96612 (MGI)
16416 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 67.84 cM Chr11:104608000-104670476 (+)
Bleeding Disorder, Platelet-Type, 16; BDPLT16
Glanzmann Thrombasthenia; GT
OTTMUSG00000003177 (VEGA)
OTTMUSP00000003116 (VEGA)
OTTMUST00000006575 (VEGA)
rat Itgb3 29302 (Entrez Gene)
Chr10 NP_714942 (RefSeq)
NM_153720 (RefSeq)
chimpanzee ITGB3 468295 (Entrez Gene)
Chr17 XP_523684 (RefSeq)
rhesus macaque ITGB3 717379 (Entrez Gene)
Chr16 XP_014974842 (RefSeq)
cattle ITGB3 282642 (Entrez Gene)
Chr19 NP_001193419 (RefSeq)
NM_001206490 (RefSeq)
dog ITGB3 403788 (Entrez Gene)
Chr9 NP_001003162 (RefSeq)
NM_001003162 (RefSeq)
chicken RP11-290H9.2 374209 (Entrez Gene)
Chr27 NP_989646 (RefSeq)
NM_204315 (RefSeq)
western clawed frog itgb3 100498495 (Entrez Gene)
ChrUN XP_002942401 (RefSeq)
zebrafish itgb3b 100001836 (Entrez Gene)
Chr12 NP_001076417 (RefSeq)
NM_001082948 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory