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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GCK HGNC:4195 (HGNC)
2645 (Entrez Gene)
138079 (OMIM)
Glucokinase (MyGene.info)
HGNC homology
Chr7 p13 Chr7:44143213-44189439 (-)
familial hyperinsulinemic hypoglycemia 3
maturity-onset diabetes of the young type 2
permanent neonatal diabetes mellitus
type 2 diabetes mellitus
P35557 (UniProt | EBI)
NM_001354802 (RefSeq)
mouse Gck MGI:1270854 (MGI)
103988 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 3.88 cM Chr11:5900820-5950081 (-)
hyperinsulinemic hypoglycemia
maturity-onset diabetes of the young type 2
type 2 diabetes mellitus
ENSMUSG00000041798 (Ensembl Gene Model)
ENSMUSP00000105448 (Ensembl)
ENSMUST00000109823 (Ensembl)
rat Gck 24385 (Entrez Gene)
Chr14 q21 P17712 (UniProt | EBI)
NM_012565 (RefSeq)
chimpanzee GCK 737923 (Entrez Gene)
Chr7 XP_016812871 (RefSeq)
cattle GCK 616576 (Entrez Gene)
Chr4 NP_001095772 (RefSeq)
NM_001102302 (RefSeq)
chicken GCK 430370 (Entrez Gene)
Chr22 XP_015157917 (RefSeq)
zebrafish gck 751668 (Entrez Gene)
Chr8 NP_001038850 (RefSeq)
NM_001045385 (RefSeq)
frog, western clawed gck 100124905 (Entrez Gene)
Chr3 NP_001096321 (RefSeq)
NM_001102851 (RefSeq)
macaque, rhesus GCK 699728 (Entrez Gene)
Chr3 XP_028701674 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory