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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
55440

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human GCK HGNC:4195 (HGNC)
2645 (Entrez Gene)
138079 (OMIM)
Chr7 p15.3-p15.1 Chr7:44144271-44189423 (-)
GRCh38
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Diabetes Mellitus, Permanent Neonatal; PNDM
Hyperinsulinemic Hypoglycemia, Familial, 3; HHF3
Maturity-Onset Diabetes of the Young, Type 2; MODY2
P35557 (UniProt | EBI)
NM_000162 (RefSeq)
mouse Gck MGI:1270854 (MGI)
103988 (Entrez Gene)
Gene Tree
VISTA-Point
Chr11 3.88 cM Chr11:5900820-5950081 (-)
GRCm38
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Hyperinsulinemic Hypoglycemia, Familial, 2; HHF2
Maturity-Onset Diabetes of the Young, Type 2; MODY2
OTTMUSG00000006327 (VEGA)
OTTMUSP00000006665 (VEGA)
OTTMUST00000014371 (VEGA)
rat Gck 24385 (Entrez Gene)
Chr14 q21 P17712 (UniProt | EBI)
NM_012565 (RefSeq)
chimpanzee GCK 737923 (Entrez Gene)
Chr7 XP_001143302 (RefSeq)
rhesus macaque GCK 699728 (Entrez Gene)
Chr3 XP_001092919 (RefSeq)
cattle GCK 616576 (Entrez Gene)
Chr4 NP_001095772 (RefSeq)
NM_001102302 (RefSeq)
chicken GCK 430370 (Entrez Gene)
Chr22 XP_427930 (RefSeq)
western clawed frog gck 100124905 (Entrez Gene)
ChrUN NP_001096321 (RefSeq)
NM_001102851 (RefSeq)
zebrafish gck 751668 (Entrez Gene)
Chr8 NP_001038850 (RefSeq)
NM_001045385 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory