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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
55437

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FGFR3 HGNC:3690 (HGNC)
2261 (Entrez Gene)
134934 (OMIM)
Chr4 p16.3 Chr4:1793299-1808872 (+)
GRCh38
Achondroplasia; ACH
Bladder Cancer
Camptodactyly, Tall Stature, and Hearing Loss Syndrome
Cervical Cancer
Colorectal Cancer; CRC
Crouzon Syndrome with Acanthosis Nigricans; CAN
Hypochondroplasia; HCH
Lacrimoauriculodentodigital Syndrome; LADD
Muenke Syndrome; MNKES
Nevus, Epidermal
Thanatophoric Dysplasia, Type I; TD1
Thanatophoric Dysplasia, Type II; TD2
P22607 (UniProt | EBI)
NM_000142 (RefSeq)
mouse Fgfr3 MGI:95524 (MGI)
14184 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 17.83 cM Chr5:33721724-33737067 (+)
GRCm38
Achondroplasia; ACH
Lung Cancer
Muenke Syndrome; MNKES
Thanatophoric Dysplasia, Type I; TD1
Thanatophoric Dysplasia, Type II; TD2
OTTMUSG00000021524 (VEGA)
OTTMUSP00000062900 (VEGA)
OTTMUST00000112075 (VEGA)
rat Fgfr3 84489 (Entrez Gene)
Chr14 q21 NP_445881 (RefSeq)
NM_053429 (RefSeq)
chimpanzee FGFR3 461067 (Entrez Gene)
Chr4 XP_003310269 (RefSeq)
rhesus macaque FGFR3 712829 (Entrez Gene)
Chr1 XP_001101016 (RefSeq)
dog FGFR3 488808 (Entrez Gene)
Chr3 XP_005618584 (RefSeq)
chicken FGFR3 396515 (Entrez Gene)
Chr4 P18460 (UniProt | EBI)
NM_205509 (RefSeq)
zebrafish fgfr3 58129 (Entrez Gene)
Chr13 Q9I8X3 (UniProt | EBI)
NM_131606 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory