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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FGFR3 HGNC:3690 (HGNC)
2261 (Entrez Gene)
134934 (OMIM)
HGNC homology
Chr4 p16.3 Chr4:1793299-1808872 (+)
Achondroplasia; ACH
Achondroplasia, Severe, with Developmental Delay and Acanthosis Nigricans;
Bladder Cancer
Camptodactyly, Tall Stature, and Hearing Loss Syndrome
Cervical Cancer
Colorectal Cancer; CRC
Crouzon Syndrome with Acanthosis Nigricans; CAN
Hypochondroplasia; HCH
Lacrimoauriculodentodigital Syndrome; LADD
Muenke Syndrome; MNKES
Nevus, Epidermal
Testicular Germ Cell Tumor; TGCT
Thanatophoric Dysplasia, Type II; TD2
Thanatophoric Dysplasia, Type I; TD1
P22607 (UniProt | EBI)
NM_000142 (RefSeq)
mouse Fgfr3 MGI:95524 (MGI)
14184 (Entrez Gene)
Gene Tree
Chr5 17.83 cM Chr5:33721674-33737067 (+)
Achondroplasia; ACH
Hypochondroplasia; HCH
Muenke Syndrome; MNKES
Thanatophoric Dysplasia, Type II; TD2
Thanatophoric Dysplasia, Type I; TD1
OTTMUSG00000021524 (VEGA)
OTTMUSP00000062900 (VEGA)
OTTMUST00000112075 (VEGA)
rat Fgfr3 84489 (Entrez Gene)
Chr14 q21 NP_445881 (RefSeq)
NM_053429 (RefSeq)
chimpanzee FGFR3 461067 (Entrez Gene)
Chr4 XP_009445506 (RefSeq)
rhesus macaque FGFR3 712829 (Entrez Gene)
Chr5 XP_014993336 (RefSeq)
cattle FGFR3 281769 (Entrez Gene)
Chr6 NP_776743 (RefSeq)
NM_174318 (RefSeq)
dog FGFR3 488808 (Entrez Gene)
Chr3 XP_005618586 (RefSeq)
chicken FGFR3 396515 (Entrez Gene)
Chr4 P18460 (UniProt | EBI)
NM_205509 (RefSeq)
western clawed frog fgfr3 100196923 (Entrez Gene)
ChrUN NP_001135467 (RefSeq)
NM_001141995 (RefSeq)
zebrafish fgfr3 58129 (Entrez Gene)
Chr13 Q9I8X3 (UniProt | EBI)
NM_131606 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory