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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AHCY HGNC:343 (HGNC)
191 (Entrez Gene)
180960 (OMIM)
HGNC homology
Chr20 q11.22 Chr20:34235012-34311976 (-)
hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase
P23526 (UniProt | EBI)
NM_001161766 (RefSeq)
mouse Ahcy MGI:87968 (MGI)
269378 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 76.94 cM Chr2:155059310-155074497 (-)
269378 (NCBI Gene Model)
P50247 (UniProt | EBI)
NM_016661 (RefSeq)
rat Ahcy 29443 (Entrez Gene)
Chr3 q41 P10760 (UniProt | EBI)
NM_017201 (RefSeq)
chimpanzee AHCY 458190 (Entrez Gene)
Chr20 NP_001267363 (RefSeq)
NM_001280434 (RefSeq)
cattle AHCY 508158 (Entrez Gene)
Chr13 Q3MHL4 (UniProt | EBI)
NM_001034315 (RefSeq)
dog AHCY 477198 (Entrez Gene)
Chr24 XP_534388 (RefSeq)
chicken AHCY 419146 (Entrez Gene)
Chr20 XP_417331 (RefSeq)
zebrafish ahcy 387530 (Entrez Gene)
Chr6 NP_954688 (RefSeq)
NM_199218 (RefSeq)
frog, western clawed ahcy 733486 (Entrez Gene)
Chr10 NP_001037894 (RefSeq)
NM_001044429 (RefSeq)
macaque, rhesus LOC698344 698344 (Entrez Gene)
Chr2 XP_001089745 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory