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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human D2HGDH HGNC:28358 (HGNC)
728294 (Entrez Gene)
609186 (OMIM)
D2HGDH (MyGene.info)
HGNC homology
Chr2 q37.3 Chr2:241734579-241768816 (+)
D-2-hydroxyglutaric aciduria 1
Q8N465 (UniProt | EBI)
NM_001352824 (RefSeq)
mouse D2hgdh MGI:2138209 (MGI)
98314 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 47.36 cM Chr1:93824909-93852348 (+)
ENSMUSG00000073609 (Ensembl Gene Model)
ENSMUSP00000108502 (Ensembl)
ENSMUST00000112881 (Ensembl)
rat D2hgdh 301624 (Entrez Gene)
Chr9 q36 P84850 (UniProt | EBI)
NM_001106926 (RefSeq)
chimpanzee D2HGDH 748707 (Entrez Gene)
Chr2B XP_024210952 (RefSeq)
cattle D2HGDH 533003 (Entrez Gene)
Chr3 Q1JPD3 (UniProt | EBI)
NM_001075978 (RefSeq)
dog D2HGDH 609641 (Entrez Gene)
Chr25 XP_005636043 (RefSeq)
chicken D2HGDH 424853 (Entrez Gene)
Chr9 XP_015132607 (RefSeq)
zebrafish d2hgdh 565889 (Entrez Gene)
Chr2 A1L258 (UniProt | EBI)
NM_001080597 (RefSeq)
frog, western clawed d2hgdh 100379761 (Entrez Gene)
Chr5 XP_004917918 (RefSeq)
macaque, rhesus D2HGDH 702028 (Entrez Gene)
Chr12 XP_014967055 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory