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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PC HGNC:8636 (HGNC)
5091 (Entrez Gene)
608786 (OMIM)
HGNC homology
Chr11 q13.2 Chr11:66848522-66958418 (-)
pyruvate carboxylase deficiency disease
P11498 (UniProt | EBI)
NM_022172 (RefSeq)
mouse Pcx MGI:97520 (MGI)
18563 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 4.07 cM Chr19:4510472-4621752 (+)
18563 (NCBI Gene Model)
Q05920 (UniProt | EBI)
NM_001162946 (RefSeq)
rat Pc 25104 (Entrez Gene)
Chr1 q43 P52873 (UniProt | EBI)
NM_012744 (RefSeq)
chimpanzee PC 451356 (Entrez Gene)
Chr11 XP_016776807 (RefSeq)
cattle PC 338471 (Entrez Gene)
Chr29 Q29RK2 (UniProt | EBI)
NM_177946 (RefSeq)
dog PC 483704 (Entrez Gene)
Chr18 XP_005631473 (RefSeq)
zebrafish pcxb 58068 (Entrez Gene)
Chr7 NP_571625 (RefSeq)
NM_131550 (RefSeq)
frog, western clawed pc.2 100125118 (Entrez Gene)
Chr4 XP_012817693 (RefSeq)
NM_001103025 (RefSeq)
macaque, rhesus PC 713103 (Entrez Gene)
Chr14 NP_001248513 (RefSeq)
NM_001261584 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory