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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
5276

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human BRCA1 HGNC:1100 (HGNC)
672 (Entrez Gene)
113705 (OMIM)
Chr17 q21 Chr17:43044295-43125483 (-)
GRCh38
Breast Cancer
Breast-Ovarian Cancer, Familial, Susceptibility to, 1; BROVCA1
Pancreatic Cancer, Susceptibility to, 4; PNCA4
P38398 (UniProt | EBI)
NM_007294 (RefSeq)
mouse Brca1 MGI:104537 (MGI)
12189 (Entrez Gene)
Gene Tree
VISTA-Point
Chr11 65.18 cM Chr11:101488764-101551955 (-)
GRCm38
Breast Cancer
Breast-Ovarian Cancer, Familial, Susceptibility to, 1; BROVCA1
OTTMUSG00000002870 (VEGA)
OTTMUSP00000002773 (VEGA)
OTTMUST00000005869 (VEGA)
rat Brca1 497672 (Entrez Gene)
Chr10 q32.1 O54952 (UniProt | EBI)
NM_012514 (RefSeq)
chimpanzee BRCA1 449497 (Entrez Gene)
Chr17 Q9GKK8 (UniProt | EBI)
NM_001045493 (RefSeq)
rhesus macaque BRCA1 712634 (Entrez Gene)
Chr16 Q6J6I9 (UniProt | EBI)
NM_001114949 (RefSeq)
cattle BRCA1 353120 (Entrez Gene)
Chr19 Q864U1 (UniProt | EBI)
NM_178573 (RefSeq)
dog BRCA1 403437 (Entrez Gene)
Chr9 Q95153 (UniProt | EBI)
NM_001013416 (RefSeq)
chicken BRCA1 373983 (Entrez Gene)
Chr27 NP_989500 (RefSeq)
NM_204169 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory