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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PNKP HGNC:9154 (HGNC)
11284 (Entrez Gene)
605610 (OMIM)
Chr19 q13.3-q13.4 Chr19:49861203-49867565 (-)
Microcephaly, Seizures, and Developmental Delay; MCSZ
Q96T60 (UniProt | EBI)
NM_007254 (RefSeq)
mouse Pnkp MGI:1891698 (MGI)
59047 (Entrez Gene)
Gene Tree
Chr7 28.94 cM Chr7:44857139-44862925 (+)
OTTMUSG00000022325 (VEGA)
OTTMUSP00000025292 (VEGA)
OTTMUST00000053209 (VEGA)
rat Pnkp 308576 (Entrez Gene)
Chr1 q22 NP_001004259 (RefSeq)
NM_001004259 (RefSeq)
chimpanzee PNKP 747683 (Entrez Gene)
Chr19 XP_009434379 (RefSeq)
rhesus macaque PNKP 719084 (Entrez Gene)
Chr19 XP_001115581 (RefSeq)
cattle PNKP 616621 (Entrez Gene)
Chr18 XP_010813532 (RefSeq)
NM_001083522 (RefSeq)
dog PNKP 484373 (Entrez Gene)
Chr1 XP_541488 (RefSeq)
western clawed frog pnkp 100145800 (Entrez Gene)
ChrUN NP_001120633 (RefSeq)
NM_001127161 (RefSeq)
zebrafish pnkp 569462 (Entrez Gene)
Chr15 NP_001071046 (RefSeq)
NM_001077578 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory