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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DOCK8 HGNC:19191 (HGNC)
81704 (Entrez Gene)
611432 (OMIM)
Dock8 (MyGene.info)
HGNC homology
Chr9 p24.3 Chr9:211297-465260 (+)
autosomal dominant non-syndromic intellectual disability 2
Q8NF50 (UniProt | EBI)
NM_001190458 (RefSeq)
mouse Dock8 MGI:1921396 (MGI)
76088 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 19.91 cM Chr19:24999529-25202432 (+)
ENSMUSG00000052085 (Ensembl Gene Model)
ENSMUSP00000025831 (Ensembl)
ENSMUST00000025831 (Ensembl)
rat Dock8 499337 (Entrez Gene)
Chr1 q51 NP_001032882 (RefSeq)
NM_001037793 (RefSeq)
chimpanzee DOCK8 473156 (Entrez Gene)
Chr9 XP_016816002 (RefSeq)
cattle DOCK8 100295817 (Entrez Gene)
Chr8 NP_001178461 (RefSeq)
NM_001191532 (RefSeq)
dog DOCK8 476333 (Entrez Gene)
Chr1 XP_005615946 (RefSeq)
chicken DOCK8 427348 (Entrez Gene)
ChrZ XP_015135634 (RefSeq)
zebrafish dock8 403040 (Entrez Gene)
Chr8 XP_021334135 (RefSeq)
frog, western clawed dock8 100488105 (Entrez Gene)
Chr1 XP_012808011 (RefSeq)
macaque, rhesus DOCK8 698081 (Entrez Gene)
Chr15 XP_014973333 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory