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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
52414

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human DOCK8 HGNC:19191 (HGNC)
81704 (Entrez Gene)
611432 (OMIM)
Chr9 p24.3 Chr9:214865-465259 (+)
GRCh38
Hyper-Ige Recurrent Infection Syndrome, Autosomal Recessive
Mental Retardation, Autosomal Dominant 2; MRD2
Q8NF50 (UniProt | EBI)
NM_203447 (RefSeq)
mouse Dock8 MGI:1921396 (MGI)
76088 (Entrez Gene)
Gene Tree
VISTA-Point
Chr19 19.91 cM Chr19:24999529-25202432 (+)
GRCm38
76088 (NCBI Gene Model)
Q8C147 (UniProt | EBI)
NM_028785 (RefSeq)
rat Dock8 499337 (Entrez Gene)
Chr1 q51 NP_001032882 (RefSeq)
NM_001037793 (RefSeq)
chimpanzee DOCK8 473156 (Entrez Gene)
Chr9 XP_003312029 (RefSeq)
rhesus macaque LOC698081 698081 (Entrez Gene)
Chr15 XP_002808151 (RefSeq)
cattle DOCK8 100295817 (Entrez Gene)
Chr8 NP_001178461 (RefSeq)
NM_001191532 (RefSeq)
dog DOCK8 476333 (Entrez Gene)
Chr1 XP_533535 (RefSeq)
chicken DOCK8 427348 (Entrez Gene)
ChrZ XP_424926 (RefSeq)
western clawed frog dock8 100488105 (Entrez Gene)
ChrUN XP_002935647 (RefSeq)
zebrafish dock8 403040 (Entrez Gene)
Chr8 XP_001920107 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory