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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ZIC2 HGNC:12873 (HGNC)
7546 (Entrez Gene)
603073 (OMIM)
HGNC homology
Chr13 q32 Chr13:99981772-99986765 (+)
Holoprosencephaly 5; HPE5
O95409 (UniProt | EBI)
NM_007129 (RefSeq)
mouse Zic2 MGI:106679 (MGI)
22772 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 65.97 cM Chr14:122475435-122479852 (+)
Holoprosencephaly 5; HPE5
Schizophrenia; SCZD
OTTMUSG00000020302 (VEGA)
OTTMUSP00000022013 (VEGA)
OTTMUST00000048178 (VEGA)
rat Zic2 361096 (Entrez Gene)
Chr15 q25 NP_001101862 (RefSeq)
NM_001108392 (RefSeq)
chimpanzee ZIC2 467311 (Entrez Gene)
Chr13 XP_003314245 (RefSeq)
rhesus macaque ZIC2 705399 (Entrez Gene)
Chr17 XP_001093759 (RefSeq)
cattle ZIC2 514433 (Entrez Gene)
Chr12 NP_001193295 (RefSeq)
NM_001206366 (RefSeq)
dog ZIC2 485533 (Entrez Gene)
Chr22 XP_542652 (RefSeq)
chicken ZIC2 428021 (Entrez Gene)
Chr1 XP_015130400 (RefSeq)
western clawed frog zic2 549779 (Entrez Gene)
ChrUN NP_001017025 (RefSeq)
NM_001017025 (RefSeq)
zebrafish zic2a 58077 (Entrez Gene)
Chr9 NP_571633 (RefSeq)
NM_131558 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory