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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SIGLEC8 HGNC:10877 (HGNC)
27181 (Entrez Gene)
605639 (OMIM)
SIGLEC8 (MyGene.info)
HGNC homology
Chr19 q13.41 Chr19:51450997-51458454 (-)
Q9NYZ4 (UniProt | EBI)
NM_014442 (RefSeq)
mouse Siglecf MGI:2681107 (MGI)
233186 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 28.25 cM Chr7:43351341-43359475 (+)
233186 (NCBI Gene Model)
Q920G3 (UniProt | EBI)
NM_145581 (RefSeq)
rat Siglec5 292843 (Entrez Gene)
Chr1 q22 NP_001099719 (RefSeq)
NM_001106249 (RefSeq)
cattle LOC618463 618463 (Entrez Gene)
Chr18 XP_002695268 (RefSeq)
dog LOC484344 484344 (Entrez Gene)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory