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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
504

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NOS3 HGNC:7876 (HGNC)
4846 (Entrez Gene)
163729 (OMIM)
Chr7 q36 Chr7:150991056-151014944 (+)
GRCh38
Alzheimer Disease; AD
Hypertension, Essential
Nitric Oxide Synthase 3; NOS3
Preeclampsia/Eclampsia 1; PEE1
Stroke, Ischemic
P29474 (UniProt | EBI)
NM_000603 (RefSeq)
mouse Nos3 MGI:97362 (MGI)
18127 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 11.32 cM Chr5:24364810-24384474 (+)
GRCm38
Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins;
Hypertension, Essential
OTTMUSG00000024082 (VEGA)
OTTMUSP00000028591 (VEGA)
OTTMUST00000058885 (VEGA)
rat Nos3 24600 (Entrez Gene)
Chr4 q11 Q62600 (UniProt | EBI)
NM_021838 (RefSeq)
chimpanzee NOS3 463893 (Entrez Gene)
Chr7 XP_003318952 (RefSeq)
rhesus macaque NOS3 714231 (Entrez Gene)
Chr3 XP_002803570 (RefSeq)
cattle NOS3 287024 (Entrez Gene)
Chr4 P29473 (UniProt | EBI)
NM_181037 (RefSeq)
dog NOS3 403784 (Entrez Gene)
Chr16 Q9TUX8 (UniProt | EBI)
NM_001003158 (RefSeq)
western clawed frog nos3 100486016 (Entrez Gene)
ChrUN NP_001243158 (RefSeq)
NM_001256229 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory