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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PRKDC HGNC:9413 (HGNC)
5591 (Entrez Gene)
600899 (OMIM)
HGNC homology
Chr8 q11.21 Chr8:47773108-47960183 (-)
Immunodeficiency 26 with or without Neurologic Abnormalities; IMD26
P78527 (UniProt | EBI)
NM_001081640 (RefSeq)
mouse Prkdc MGI:104779 (MGI)
19090 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 10.09 cM Chr16:15637866-15842235 (+)
Severe Combined Immunodeficiency, Autosomal Recessive, T Cell-Negative, B Cell-Negative, Nk Cell-Positive
OTTMUSG00000043440 (VEGA)
OTTMUSP00000063630 (VEGA)
OTTMUST00000113952 (VEGA)
rat Prkdc 360748 (Entrez Gene)
Chr11 q23 XP_003752582 (RefSeq)
NM_001108327 (RefSeq)
chimpanzee PRKDC 464165 (Entrez Gene)
Chr8 XP_519750 (RefSeq)
cattle PRKDC 512740 (Entrez Gene)
Chr14 NP_001243488 (RefSeq)
NM_001256559 (RefSeq)
dog PRKDC 474176 (Entrez Gene)
Chr29 Q8WN22 (UniProt | EBI)
NM_001006651 (RefSeq)
chicken PRKDC 395376 (Entrez Gene)
Chr2 Q8QGX4 (UniProt | EBI)
NM_204658 (RefSeq)
zebrafish prkdc 562283 (Entrez Gene)
Chr7 XP_009301676 (RefSeq)
frog, western clawed prkdc 100488663 (Entrez Gene)
Chr6 XP_012820747 (RefSeq)
macaque, rhesus PRKDC 708029 (Entrez Gene)
Chr8 XP_015000814 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.06
The Jackson Laboratory