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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IL6 HGNC:6018 (HGNC)
3569 (Entrez Gene)
147620 (OMIM)
Interleukin 6 (MyGene.info)
HGNC homology
Chr7 p15.3 Chr7:22725889-22732002 (+)
arteriovenous malformations of the brain
juvenile rheumatoid arthritis
Kaposi's sarcoma
P05231 (UniProt | EBI)
NM_000600 (RefSeq)
mouse Il6 MGI:96559 (MGI)
16193 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 15.7 cM Chr5:30013114-30019981 (+)
OTTMUSG00000054480 (VEGA)
OTTMUSP00000071554 (VEGA)
OTTMUST00000135092 (VEGA)
rat Il6 24498 (Entrez Gene)
Chr4 q11 P20607 (UniProt | EBI)
NM_012589 (RefSeq)
chimpanzee IL6 463288 (Entrez Gene)
Chr7 XP_016801024 (RefSeq)
dog IL6 403985 (Entrez Gene)
Chr14 P41323 (UniProt | EBI)
NM_001003301 (RefSeq)
chicken IL6 395337 (Entrez Gene)
Chr2 Q90YI0 (UniProt | EBI)
NM_204628 (RefSeq)
macaque, rhesus IL6 705819 (Entrez Gene)
Chr3 P51494 (UniProt | EBI)
NM_001042733 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory