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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPINK5 HGNC:15464 (HGNC)
11005 (Entrez Gene)
605010 (OMIM)
LEKTI (MyGene.info)
HGNC homology
Chr5 q32 Chr5:148063972-148137362 (+)
Netherton syndrome
Q9NQ38 (UniProt | EBI)
NM_001127699 (RefSeq)
mouse Spink5 MGI:1919682 (MGI)
72432 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 23.74 cM Chr18:43963235-44022501 (+)
Netherton syndrome
OTTMUSG00000016338 (VEGA)
OTTMUSP00000017545 (VEGA)
OTTMUST00000039263 (VEGA)
rat LOC100910851 100910851 (Entrez Gene)
Chr1 XP_003749120 (RefSeq)
Spink5 361319 (Entrez Gene)
Chr18 p11 NP_001164077 (RefSeq)
NM_001170606 (RefSeq)
chimpanzee SPINK5 462173 (Entrez Gene)
Chr5 XP_001160618 (RefSeq)
cattle SPINK5 526637 (Entrez Gene)
Chr7 NP_001095572 (RefSeq)
NM_001102102 (RefSeq)
dog SPINK5 478055 (Entrez Gene)
Chr2 NP_001020568 (RefSeq)
NM_001025397 (RefSeq)
chicken SPIK5 416235 (Entrez Gene)
Chr13 P10184 (UniProt | EBI)
NM_001030612 (RefSeq)
SPIK7 416236 (Entrez Gene)
Chr13 P01005 (UniProt | EBI)
NM_001112662 (RefSeq)
macaque, rhesus SPINK5 709424 (Entrez Gene)
Chr6 XP_014996686 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory