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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
496

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TNF HGNC:11892 (HGNC)
7124 (Entrez Gene)
191160 (OMIM)
Chr6 p21.3 Chr6:31575567-31578336 (+)
GRCh38
Asthma, Susceptibility to
Malaria, Susceptibility to
Migraine with or without Aura, Susceptibility to, 1
P01375 (UniProt | EBI)
NM_000594 (RefSeq)
mouse Tnf MGI:104798 (MGI)
21926 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 18.59 cM Chr17:35199381-35202007 (-)
GRCm38
Rheumatoid Arthritis; RA
OTTMUSG00000037196 (VEGA)
OTTMUSP00000053529 (VEGA)
OTTMUST00000095888 (VEGA)
rat Tnf 24835 (Entrez Gene)
Chr20 p12 P16599 (UniProt | EBI)
NM_012675 (RefSeq)
chimpanzee TNF 494186 (Entrez Gene)
Chr6 Q8HZD9 (UniProt | EBI)
NM_001045511 (RefSeq)
rhesus macaque TNF 715467 (Entrez Gene)
Chr4 P48094 (UniProt | EBI)
NM_001047149 (RefSeq)
cattle TNF 280943 (Entrez Gene)
Chr23 q22 Q06599 (UniProt | EBI)
NM_173966 (RefSeq)
dog TNF 403922 (Entrez Gene)
Chr12 P51742 (UniProt | EBI)
NM_001003244 (RefSeq)
western clawed frog tnf 100134991 (Entrez Gene)
ChrUN NP_001107143 (RefSeq)
NM_001113671 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory