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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AFG3L2 HGNC:315 (HGNC)
10939 (Entrez Gene)
604581 (OMIM)
AFG3L2 (MyGene.info)
HGNC homology
Chr18 p11.21 Chr18:12328944-12377309 (-)
spastic ataxia 5
spinocerebellar ataxia type 28
Q9Y4W6 (UniProt | EBI)
NM_006796 (RefSeq)
mouse Afg3l2 MGI:1916847 (MGI)
69597 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 39.96 cM Chr18:67404760-67449136 (-)
spinocerebellar ataxia type 28
69597 (NCBI Gene Model)
Q8JZQ2 (UniProt | EBI)
NM_027130 (RefSeq)
rat Afg3l2 307350 (Entrez Gene)
Chr18 q12.1 NP_001128336 (RefSeq)
NM_001013140 (RefSeq)
chimpanzee AFG3L2 455507 (Entrez Gene)
Chr18 XP_016788766 (RefSeq)
cattle AFG3L2 515757 (Entrez Gene)
Chr24 Q2KJI7 (UniProt | EBI)
NM_001046211 (RefSeq)
dog AFG3L2 490560 (Entrez Gene)
Chr7 XP_022277351 (RefSeq)
chicken AFG3L2 421036 (Entrez Gene)
Chr2 XP_004939781 (RefSeq)
zebrafish afg3l2 569168 (Entrez Gene)
Chr2 NP_001104667 (RefSeq)
NM_001111197 (RefSeq)
frog, western clawed afg3l2 780216 (Entrez Gene)
Chr6 NP_001072759 (RefSeq)
NM_001079291 (RefSeq)
macaque, rhesus AFG3L2 703079 (Entrez Gene)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory