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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LEFTY1 HGNC:6552 (HGNC)
10637 (Entrez Gene)
603037 (OMIM)
HGNC homology
Chr1 q42.12 Chr1:225886282-225889146 (-)
O75610 (UniProt | EBI)
NM_020997 (RefSeq)
mouse Lefty1 MGI:107405 (MGI)
13590 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 84.46 cM Chr1:180935022-180938400 (+)
ENSMUSG00000038793 (Ensembl Gene Model)
ENSMUSP00000041427 (Ensembl)
ENSMUST00000037361 (Ensembl)
rat Lefty1 498299 (Entrez Gene)
Chr13 q26 NP_001102550 (RefSeq)
NM_001109080 (RefSeq)
chimpanzee LEFTY1 737178 (Entrez Gene)
Chr1 XP_001138066 (RefSeq)
macaque, rhesus LOC699924 699924 (Entrez Gene)
Chr1 XP_014970690 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory