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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AKT2 HGNC:392 (HGNC)
208 (Entrez Gene)
164731 (OMIM)
HGNC homology
Chr19 q13.1-q13.2 Chr19:40230317-40285531 (-)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Hypoinsulinemic Hypoglycemia with Hemihypertrophy; HIHGHH
P31751 (UniProt | EBI)
NM_001243027 (RefSeq)
mouse Akt2 MGI:104874 (MGI)
11652 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 15.94 cM Chr7:27591552-27640826 (+)
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Polycystic Ovary Syndrome 1; PCOS1
OTTMUSG00000016504 (VEGA)
OTTMUSP00000017783 (VEGA)
OTTMUST00000039864 (VEGA)
rat Akt2 25233 (Entrez Gene)
Chr1 q22 P47197 (UniProt | EBI)
NM_017093 (RefSeq)
chimpanzee AKT2 456035 (Entrez Gene)
Chr19 XP_009433874 (RefSeq)
rhesus macaque AKT2 700591 (Entrez Gene)
Chr19 NP_001252918 (RefSeq)
NM_001265989 (RefSeq)
cattle AKT2 534923 (Entrez Gene)
Chr18 NP_001193075 (RefSeq)
NM_001206146 (RefSeq)
dog AKT2 449021 (Entrez Gene)
Chr1 NP_001012340 (RefSeq)
NM_001012340 (RefSeq)
western clawed frog akt2 100144709 (Entrez Gene)
ChrUN NP_001116936 (RefSeq)
NM_001123464 (RefSeq)
zebrafish akt2 378972 (Entrez Gene)
Chr18 NP_937789 (RefSeq)
NM_198146 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory