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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MAP2K2 HGNC:6842 (HGNC)
5605 (Entrez Gene)
601263 (OMIM)
MAP2K2 (MyGene.info)
HGNC homology
Chr19 p13.3 Chr19:4090321-4124184 (-)
cardiofaciocutaneous syndrome
P36507 (UniProt | EBI)
NM_030662 (RefSeq)
mouse Map2k2 MGI:1346867 (MGI)
26396 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 39.72 cM Chr10:81105912-81124697 (+)
26396 (NCBI Gene Model)
Q63932 (UniProt | EBI)
NM_001358539 (RefSeq)
rat Map2k2 58960 (Entrez Gene)
Chr7 q11 P36506 (UniProt | EBI)
NM_133283 (RefSeq)
chimpanzee LOC100611792 100611792 (Entrez Gene)
cattle MAP2K2 510434 (Entrez Gene)
Chr7 NP_001033160 (RefSeq)
NM_001038071 (RefSeq)
dog MAP2K2 611939 (Entrez Gene)
Chr20 Q1HG70 (UniProt | EBI)
NM_001048136 (RefSeq)
chicken MAP2K2 396349 (Entrez Gene)
Chr28 Q90891 (UniProt | EBI)
NM_205388 (RefSeq)
zebrafish map2k2a 563181 (Entrez Gene)
Chr22 NP_001032468 (RefSeq)
NM_001037391 (RefSeq)
map2k2b 100002225 (Entrez Gene)
Chr2 NP_001121753 (RefSeq)
NM_001128281 (RefSeq)
macaque, rhesus MAP2K2 721821 (Entrez Gene)
Chr19 XP_014977979 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory