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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human WDR45 HGNC:28912 (HGNC)
11152 (Entrez Gene)
300526 (OMIM)
HGNC homology
ChrX p11.23 ChrX:49074433-49101121 (-)
Neurodegeneration with Brain Iron Accumulation 5; NBIA5
Q9Y484 (UniProt | EBI)
NM_007075 (RefSeq)
mouse Wdr45 MGI:1859606 (MGI)
54636 (Entrez Gene)
Gene Tree
ChrX 3.48 cM ChrX:7721973-7728201 (+)
OTTMUSG00000017803 (VEGA)
OTTMUSP00000019385 (VEGA)
OTTMUST00000043104 (VEGA)
chimpanzee WDR45 465626 (Entrez Gene)
ChrX XP_009437337 (RefSeq)
rhesus macaque WDR45 715262 (Entrez Gene)
ChrX NP_001253949 (RefSeq)
NM_001267020 (RefSeq)
cattle WDR45 539190 (Entrez Gene)
ChrX NP_001069619 (RefSeq)
NM_001076151 (RefSeq)
dog WDR45 612890 (Entrez Gene)
ChrX XP_005641402 (RefSeq)
western clawed frog wdr45 496788 (Entrez Gene)
ChrUN NP_001011326 (RefSeq)
NM_001011326 (RefSeq)
zebrafish wdr45 393200 (Entrez Gene)
Chr10 Q7ZUX3 (UniProt | EBI)
NM_200231 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory