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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RAF1 HGNC:9829 (HGNC)
5894 (Entrez Gene)
164760 (OMIM)
C-Raf (MyGene.info)
HGNC homology
Chr3 p25.2 Chr3:12583601-12664201 (-)
dilated cardiomyopathy 1NN
LEOPARD syndrome
Noonan syndrome 5
P04049 (UniProt | EBI)
NM_001354695 (RefSeq)
mouse Raf1 MGI:97847 (MGI)
110157 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 53.62 cM Chr6:115618067-115676635 (-)
Noonan syndrome 5
OTTMUSG00000020697 (VEGA)
OTTMUSP00000022609 (VEGA)
OTTMUST00000048985 (VEGA)
rat Raf1 24703 (Entrez Gene)
Chr4 q42 P11345 (UniProt | EBI)
NM_012639 (RefSeq)
chimpanzee RAF1 460182 (Entrez Gene)
Chr3 XP_024211106 (RefSeq)
dog RAF1 484648 (Entrez Gene)
Chr20 XP_022262065 (RefSeq)
chicken RAF1 396245 (Entrez Gene)
Chr12 P05625 (UniProt | EBI)
NM_205307 (RefSeq)
zebrafish raf1b 557109 (Entrez Gene)
Chr11 NP_001186684 (RefSeq)
NM_001199755 (RefSeq)
frog, western clawed raf1 549871 (Entrez Gene)
ChrUN NP_001017117 (RefSeq)
NM_001017117 (RefSeq)
macaque, rhesus RAF1 694725 (Entrez Gene)
Chr2 NP_001253231 (RefSeq)
NM_001266302 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory