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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C8B HGNC:1353 (HGNC)
732 (Entrez Gene)
120960 (OMIM)
HGNC homology
Chr1 p32.2 Chr1:56929210-56974383 (-)
type II complement component 8 deficiency
P07358 (UniProt | EBI)
NM_000066 (RefSeq)
mouse C8b MGI:88236 (MGI)
110382 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 48.61 cM Chr4:104766317-104804548 (+)
OTTMUSG00000008115 (VEGA)
OTTMUSP00000008473 (VEGA)
OTTMUST00000018444 (VEGA)
rat C8b 313421 (Entrez Gene)
Chr5 q34 P55314 (UniProt | EBI)
NM_001191759 (RefSeq)
chimpanzee C8B 456887 (Entrez Gene)
Chr1 XP_009457007 (RefSeq)
cattle C8B 513217 (Entrez Gene)
Chr3 NP_001039606 (RefSeq)
NM_001046141 (RefSeq)
dog C8B 479555 (Entrez Gene)
Chr5 XP_536694 (RefSeq)
chicken C8B 424669 (Entrez Gene)
Chr8 NP_001308472 (RefSeq)
NM_001321543 (RefSeq)
zebrafish c8b 793127 (Entrez Gene)
Chr2 NP_001243652 (RefSeq)
NM_001256723 (RefSeq)
frog, western clawed c8b 100380076 (Entrez Gene)
Chr4 XP_002931633 (RefSeq)
macaque, rhesus C8B 716155 (Entrez Gene)
Chr1 XP_001114456 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory