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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FXN HGNC:3951 (HGNC)
2395 (Entrez Gene)
606829 (OMIM)
Frataxin (MyGene.info)
HGNC homology
Chr9 q21.11 Chr9:69035563-69100178 (+)
Q16595 (UniProt | EBI)
NM_181425 (RefSeq)
mouse Fxn MGI:1096879 (MGI)
14297 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 19.39 cM Chr19:24261453-24280586 (-)
Friedreich ataxia
14297 (NCBI Gene Model)
O35943 (UniProt | EBI)
NR_157400 (RefSeq)
rat Fxn 499335 (Entrez Gene)
Chr1 q51 D3ZYW7 (UniProt | EBI)
NM_001191952 (RefSeq)
chimpanzee FXN 737660 (Entrez Gene)
Chr9 XP_016816420 (RefSeq)
cattle FXN 505694 (Entrez Gene)
Chr8 Q05B87 (UniProt | EBI)
NM_001080727 (RefSeq)
dog FXN 609051 (Entrez Gene)
Chr1 NP_001103428 (RefSeq)
NM_001109958 (RefSeq)
chicken FXN 427244 (Entrez Gene)
ChrZ XP_424827 (RefSeq)
zebrafish fxn 556389 (Entrez Gene)
Chr8 NP_001076485 (RefSeq)
NM_001083016 (RefSeq)
frog, western clawed fxn 100497789 (Entrez Gene)
Chr1 XP_002934226 (RefSeq)
macaque, rhesus FXN 699469 (Entrez Gene)
Chr15 NP_001247670 (RefSeq)
NM_001260741 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory