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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ESR1 HGNC:3467 (HGNC)
2099 (Entrez Gene)
133430 (OMIM)
Estrogen receptor alpha (MyGene.info)
HGNC homology
Chr6 q25.1-q25.2 Chr6:151654148-152103274 (+)
breast cancer
myocardial infarction
P03372 (UniProt | EBI)
NM_001291241 (RefSeq)
mouse Esr1 MGI:1352467 (MGI)
13982 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 2.03 cM Chr10:4611593-5005614 (+)
breast cancer
OTTMUSG00000020886 (VEGA)
OTTMUSP00000022868 (VEGA)
OTTMUST00000049380 (VEGA)
rat Esr1 24890 (Entrez Gene)
Chr1 q11 P06211 (UniProt | EBI)
NM_012689 (RefSeq)
chimpanzee ESR1 463079 (Entrez Gene)
Chr6 XP_003311597 (RefSeq)
cattle ESR1 407238 (Entrez Gene)
Chr9 P49884 (UniProt | EBI)
NM_001001443 (RefSeq)
dog ESR1 403640 (Entrez Gene)
Chr1 NP_001273887 (RefSeq)
NM_001286958 (RefSeq)
chicken ESR1 396099 (Entrez Gene)
Chr3 P06212 (UniProt | EBI)
NM_205183 (RefSeq)
zebrafish esr1 259252 (Entrez Gene)
Chr20 P57717 (UniProt | EBI)
NM_152959 (RefSeq)
frog, western clawed esr1 394461 (Entrez Gene)
Chr5 NP_988866 (RefSeq)
NM_203535 (RefSeq)
macaque, rhesus ESR1 613025 (Entrez Gene)
Chr4 P49886 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory