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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IL10 HGNC:5962 (HGNC)
3586 (Entrez Gene)
124092 (OMIM)
Interleukin 10 (MyGene.info)
HGNC homology
Chr1 q32.1 Chr1:206767603-206772494 (-)
acquired immunodeficiency syndrome
rheumatoid arthritis
P22301 (UniProt | EBI)
NM_000572 (RefSeq)
mouse Il10 MGI:96537 (MGI)
16153 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 56.89 cM Chr1:131019845-131024970 (+)
inflammatory bowel disease
16153 (NCBI Gene Model)
P18893 (UniProt | EBI)
NM_010548 (RefSeq)
rat Il10 25325 (Entrez Gene)
Chr13 q13 P29456 (UniProt | EBI)
NM_012854 (RefSeq)
chimpanzee IL10 469657 (Entrez Gene)
Chr1 A2T6Z6 (UniProt | EBI)
NM_001135620 (RefSeq)
cattle IL10 281246 (Entrez Gene)
Chr16 P43480 (UniProt | EBI)
NM_174088 (RefSeq)
dog IL10 403628 (Entrez Gene)
Chr7 P48411 (UniProt | EBI)
NM_001003077 (RefSeq)
chicken IL10 428264 (Entrez Gene)
Chr26 Q6A2H4 (UniProt | EBI)
NM_001004414 (RefSeq)
zebrafish il10 553957 (Entrez Gene)
Chr11 NP_001018621 (RefSeq)
NM_001020785 (RefSeq)
frog, western clawed il10 100335053 (Entrez Gene)
Chr2 NP_001165400 (RefSeq)
NM_001171929 (RefSeq)
macaque, rhesus IL10 694931 (Entrez Gene)
Chr1 P51496 (UniProt | EBI)
NM_001044727 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory