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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C8A HGNC:1352 (HGNC)
731 (Entrez Gene)
120950 (OMIM)
HGNC homology
Chr1 p32 Chr1:56854770-56918221 (+)
Complement Component 8 Deficiency, Type I; C8D1
P07357 (UniProt | EBI)
NM_000562 (RefSeq)
mouse C8a MGI:2668347 (MGI)
230558 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 48.69 cM Chr4:104815679-104876398 (-)
OTTMUSG00000008116 (VEGA)
OTTMUSP00000008475 (VEGA)
OTTMUST00000018447 (VEGA)
rat C8a 298288 (Entrez Gene)
Chr5 q34 NP_001100140 (RefSeq)
NM_001106670 (RefSeq)
chimpanzee C8A 456886 (Entrez Gene)
Chr1 XP_009456990 (RefSeq)
rhesus macaque C8A 716114 (Entrez Gene)
Chr1 XP_001114403 (RefSeq)
cattle C8A 527391 (Entrez Gene)
Chr3 NP_001039750 (RefSeq)
NM_001046285 (RefSeq)
dog C8A 100855712 (Entrez Gene)
Chr5 XP_003639070 (RefSeq)
chicken C8A 429111 (Entrez Gene)
Chr8 XP_426667 (RefSeq)
western clawed frog c8a 448034 (Entrez Gene)
ChrUN NP_001005445 (RefSeq)
NM_001005445 (RefSeq)
zebrafish c8a 445102 (Entrez Gene)
Chr2 NP_001003496 (RefSeq)
NM_001003496 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory